This Comic's Storylines:

Now I'm not going to pretend that CVRPG is a scientifically accurate comic. We have vampires and magic and golems and angels. It's just not accurate. Still, occasionally I do put in the effort to try and ground the comic in reality some.

In this case, the map of the space sectors is relatively accurate. The stars in the graphic are a little big, but the orbs are a decently accurate depiction of the range of the Kuiper belt around each star (assuming Alpha Centauri has a Kuiper belt of some kind, which is an educated guess I'm willing to make). Alpha Centauri is a little over 4 light years away from us, and our star's own Oort cloud (outermost layer of our solar system, from which comets theoretically orbit in) reaches about 3.2 light years out from our sun.
Taking all that into account (and referencing various graphics I found online) the general positioning of the two stars is about as accurate as I can make it in a shitty comic about cowardly heroes always running from danger.

When evil spreads across the land, and darkness rises and the monsters roam. When the creatures of the night make beautiful music, and the things that go bump in the night go bump with greater enthusiasm. When the world is in peril and is in need of a hero...

These guys are, sadly, the best the world can hope for. These are the adventures of the heroes of CVRPG. They mean well, they try hard, and occasionally they do the impossible...

They actually do something heroic.