This Comic's Cast:

I'm not certain we ever have actual vampires in the Mario series. Just about ever genre is touched on by that whole series, but not all of the entries are in continuity, and even if one with a vampire is in cannon, it may not have actually be called a "vampire" so I feel pretty safe here.

Besides, this is likely taking place during Mario 3, and I doubt a vampire character showed up before then. Good to go.
 
Raposa
2015-11-23 19:45:27 
Well, there was Count Bleck from the Paper Mario series.. he was kind of vampire-like.
    

When evil spreads across the land, and darkness rises and the monsters roam. When the creatures of the night make beautiful music, and the things that go bump in the night go bump with greater enthusiasm. When the world is in peril and is in need of a hero...

These guys are, sadly, the best the world can hope for. These are the adventures of the heroes of CVRPG. They mean well, they try hard, and occasionally they do the impossible...

They actually do something heroic.