If you're wondering, they're in a Metroid game currently. I think it's Metroid Fusion, but I'd have to go back and check... and we all know that's not going to happen.

If the comic followed proper timelines, Alucard wouldn't know about the Chaos realm yet. Of course, if the comic followed proper timelines, it's unlikely Alucard and Simon would be hanging out. Yes, Alucard is effectively immortal, and would have been around when Simon was alive (as Alucard knew Simon's ancestor, Sonia), but I believe Alucard was taking a long dirt nap while Simon was around (to try and rid the world of his family's cursed blood).

Sadly, I know way too much about Castlevania continuity.
 
    

When evil spreads across the land, and darkness rises and the monsters roam. When the creatures of the night make beautiful music, and the things that go bump in the night go bump with greater enthusiasm. When the world is in peril and is in need of a hero...

These guys are, sadly, the best the world can hope for. These are the adventures of the heroes of CVRPG. They mean well, they try hard, and occasionally they do the impossible...

They actually do something heroic.